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SSM Health St. Mary's Hospital - Jefferson City

2505 Mission Drive
Jefferson City, MO  65109

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Located in Missouri's state capitol for more than 100 years, SSM Health St. Mary’s Hospital - Jefferson City is a full-service, community hospital with a rich history. The hospital moved to a new state-of-the-art building in 2014 and features an evidence-based design that focuses on healing environments and patient safety. We serve patients in need of emergency, cardiology, orthopedic, cancer, maternity and medical imaging services. 

We consistently offer the latest advances in medical services to provide our patients with exceptional health care. With an emphasis on privacy, safety, efficiency, access and healing, you’ll notice the SSM Health difference from the moment you enter our facilities.​​​ 

Plan your visit to St. Mary’s Hospital - Jefferson City

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SSM Health St. Mary's Hospital Jefferson City Missouri

SSM Health Spine & Back Center patient Sue Locke

Spine & Pain Management

Relieve Back Pain With Minimally Invasive Surgery

The SSM Health Spine and Pain Management Center provides you with a full array of solutions for a healthier spine. 

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Blessed Beginnings

Our birthing center is the perfect place to experience the arrival of your blessed miracle.

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It's moments like this.

The Healing Power of Presence.

The better we know you as a person, the better we can treat you as a patient.

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Spine & Pain

​​​​​​​​​​​​​​​​Consult with top pain management physicians, spine surgeons and rehabilitation specialists to overcome pain and get back to enjoying life.


From NICU consults to advanced stroke care, our telehealth services use innovative technology to expand access to specialized medical care throughout Missouri.


Bone fractures, tumors, blood clots and more, we use the best diagnostic tools to produce detailed images that help radiologists detect problems and quickly report them to your physician.


Our physicians specialize in diseases of the lungs and bronchial tubes and offer treatment for many respiratory diseases and illnesses, including emphysema, bronchitis and COPD.


Find the most advanced cardiology care including surgical treatment of heart conditions in Mid-Missouri at SSM Health St. Mary's Hospital - Jefferson City.

Emergency & Urgent Care

You're hurt. You're sick. Your doctor is not available. Luckily, with SSM H​​​​ealth Urgent Care or Walk-In Clinic, you can get the treatment you need now. We even offer convenient online scheduling.

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