SSM Health and the healing power of presence

SSM Health St. Mary's Hospital - St. Louis

6420 Clayton Road
St. Louis, MO  63117

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SSM Health St. Mary’s Hospital - St. Louis is a two-time winner of the Premier Award for Quality and a Level I Time Critical Diagnosis STEMI Center. Centrally located in metro St. Louis, we provide exceptional care to all our patients and specialize in heart attack care, high-risk pregnancy care and fetal surgery. Plus, our chest pain center, advanced stroke care, imaging and outpatient services give you the needed reassurance to know you’re well taken care of. 

We also operate as a teaching hospital, offering an independent, accredited internal medicine residency program. We serve as the primary location for St. Louis University School of Medicine’s Department of Obstetrics and Gynecology and its Family Practice Residency programs. 

Plan your visit to St. Mary’s Hospital – St. Louis

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SSM Health St. Mary's Hospital St. Louis Missouri

woman admiring pregnant belly

High-Risk Pregnancy Care

Experts In Maternal-Fetal Medicine

Our high-risk pregnancy center is home to the nation’s leading OB care for high-risk moms and babies. We are fully equipped with a Level III Neonatal ICU, a Perinatal Center and a satellite location for the SSM Health Cardinal Glennon Fetal Care Institute.

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Quality Patient Care

St. Mary’s Hospital was recognized by Premier, Inc. reducing preventable hospital-acquired conditions and readmissions, as part of their participation during the federal Partnership for Patients Hospital Engagement Network 2.0 initiative.

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It's moments like this.

The Healing Power of Presence.

The better we know you as a person, the better we can treat you as a patient.

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Pregnancy & Baby

Delivering more than 3,000 babies per year, St. Mary's Hospital - St. Louis provides mothers with a range of childbirth options. We also provide an experienced staff able to handle the most critical pregnancies and births. 


SSM Health Neurosciences combines the skills of dozens of neurologists, neurosurgeons, neuro-interventionalists and pain specialists to diagnose and treat a variety of neurological health conditions, including movement disorders, stroke and concussions.

Heart & Vascular

Your heart will beat 2.5 billion times during your lifetime. Your heart deserves the most progressive care from the most experienced heart team in the region – SSM Health Heart & Vascular.

Women's Health

No matter what stage of life you’re in, if you’re looking to start a family or seeking general care, we provide comprehensive health care to help you make the most informed decisions.


The Knee and Hip Center at St. Mary’s Hospital - St. Louis, which opened in 1998, is a dedicated unit for knee, hip and shoulder joint replacement surgery.

Behavioral Health

St. Mary’s Hospital - St. Louis offers inpatient  and outpatient care for adults and seniors who are experiencing acute psychiatric problems.

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