Whole Exome Analysis of Patients with Renal Anomalies Study

The Cardinal Glennon St. Louis Fetal Care Institute is enrolling patients to voluntarily participate in renal (kidney) anomaly study being conducted by Saint Louis University in conjunction with SSM Health Cardinal Glennon Children’s Hospital and Washington University.

When a baby is diagnosed with a kidney or urinary tract abnormality during pregnancy, the baby, mom, and dad can enroll in this study that will analyze DNA via whole exome sequencing. The baby’s genes will be compared to the parents’ genes, in hopes of identifying the genes that cause the renal anomaly. If there is an additional family member (grandparent, sibling, aunt, uncle, etc.) with a history of renal abnormalities, they can also enroll in the study. A sample of either blood, amniotic fluid (if an amniocentesis is performed for regular care), or a cheek swab will be obtained from each person one time and sent for whole exome sequencing analysis. Individual results will not be provided, but we will publish information from the study to help researchers care for others who have a kidney or urinary tract diagnosis.

For additional details, email the Cardinal Glennon Fetal Care Institute or call 314-268-4037.